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butabarbital will lessen the level or result of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Effect of coadministering a solid CYP3A4 inducer with fedratinib hasn't been researched.Barbiturates ended up initial found out to get medical use in 1903, each time a research at Bayer showed ba